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RETATRUTIDE Triple Agonist 18mg / vial ≥99% PURITY PRIME 9 LABS
HPLC Verified
COA Included
Same-Day Ship
US Tested
Metabolic Peptides

Retatrutide

LY3437943 · Triple GIP/GLP-1/Glucagon Agonist · Lyophilized Powder

$125
per vial · 18mg
≥99% Purity
3rd Party Tested
COA Available
Sterility Tested
Molecular Weight
~4,700 Da
CAS Number
2381722-44-5
Targets
GIP · GLP-1 · Gcg

Retatrutide is a next-generation triple receptor agonist targeting GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon receptors simultaneously. Studied in the context of metabolic syndrome, obesity-related pathways, and energy homeostasis research.

Size

For Research Use Only · Not for Human Consumption

Product Overview

Retatrutide (LY3437943) is a novel unimolecular triple agonist developed for research into complex metabolic pathways. Unlike single or dual agonists, Retatrutide simultaneously engages three distinct receptor systems, making it an important compound for researchers studying overlapping metabolic signaling networks.

Prime 9 Labs supplies Retatrutide as a lyophilized powder at ≥99% purity confirmed by HPLC analysis. Each batch undergoes independent third-party testing at accredited U.S. laboratories. A batch-specific COA is included with every order.

Compound Details

  • Classification: Polypeptide / Triple receptor agonist
  • Targets: GIP receptor, GLP-1 receptor, Glucagon receptor
  • Approximate molecular weight: ~4,700 Da
  • CAS Number: 2381722-44-5
  • Form: Lyophilized white powder
  • Storage: −20°C, avoid light and moisture

Research Background

Retatrutide represents one of the most advanced peptide compounds under investigation for metabolic research. By engaging three independent receptor pathways, researchers can study how concurrent stimulation of GIP, GLP-1, and glucagon receptors influences energy balance and substrate metabolism.

Areas of Study

  • Multi-receptor metabolic signaling and pathway cross-talk
  • Energy expenditure and substrate utilization in cell models
  • Adipose tissue remodeling and lipid metabolism
  • Pancreatic beta-cell function and insulin secretion dynamics
  • Glucagon counter-regulatory mechanisms
  • Obesity pathway and appetite-regulatory network research

For research purposes only. Consult institutional protocols and peer-reviewed literature before use.

Certificate of Analysis: Batch #P9-RET-2601

TestMethodSpecificationResultStatus
AppearanceVisualWhite lyophilized powderConformsPASS
HPLC PurityHPLC-UV≥99.0%99.3%PASS
MS IdentityLC-MS/MSTheoretical MW ±1%ConformsPASS
Heavy MetalsICP-MS<10 ppm total<3 ppmPASS
EndotoxinLAL<5 EU/mg<1 EU/mgPASS
SterilityUSP <71>No growthNo growthPASS
Water ContentKarl Fischer<5%3.1%PASS

Testing performed by accredited U.S. third-party laboratory. Full COA PDF available upon request.